Marmaduke

Marmaduke is a movie starring Owen Wilson, Judy Greer, and Lee Pace. A suburban family moves to a new neighborhood with their large, yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way.
When Phil and Debbie Winslow relocate from their native Kansas to the sunny climes of Orange County, their big-hearted, havoc-wreaking Great Dane gets a taste of the dog's life, California-style.